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  URSOLIC ACID 
Artikel nr: 113

Reverse Atrophy  - Enhance Hypertrophy
Reducerar muskelförtvining och ökar muskeltillväxt



Muskelförtvining är idag ett stort problem och något som forskare ägnar mycket tid åt att lösa. I och med en omfattande studie* gjord på ett universitet i Iowa, USA, har man gjort ett stort genombrott genom att identifiera
de gener som aktiverades vid muskelförtvining. Genom att studera genaktiviteten hittade man ämnen som kunde blockera muskelförtviningen. Ett av dessa var särskilt intressant, Ursolic acid (ursolsyra), som framförallt finns koncentrerat i äpplen.

Genom fortsatt forskning fann man att ursolic acid ökade både styrkan och storleken på muskelfibrerna. Ursolic Acid hade även andra fördelar t.ex. reducerat kroppsfett och sänkt kolesterolhalt. 

I den uppföljande forskningen visades att Ursolic acid skyddade från muskelförtvining som framkallats av både svält och sjukdom. Dessutom utvecklades större och starkare muskler

Fördelar med Ursolic acid:
- Anti-katabolt
- Muskelbyggande
- Fettförbrännande
- Anti-aromatiskt**
- Naturlig produkt

U-Grow är dopingtestad av Eurofins Food & Agro Sweden AB i Lidköping. Ladda ner Analysen

Innehåll: Ursolsyraextrakt 25% 
Dosering: 6 kapslar/ dag ger 1200mg ursolsyraextrakt. Tas i samband med måltid 
Förpackning : 120 kapslar per burk
Portioner: 20 portioner á 6 kapslar
 


Ladda ner större bild

* 1: mRNA expression signatures of human skeletal muscle atrophy identify a natural compound that increases muscle mass.
Kunkel SD, Suneja M, Ebert SM, Bongers KS, Fox DK, Malmberg SE, Alipour F, Shields RK, Adams CM.
SourceDepartment of Internal Medicine, Roy J. and Lucille A. Carver College of Medicine, The University of Iowa, Iowa City, IA 52242, USA.

** Eur J Med Chem. 2008 Sep;43(9):1865-77. Epub 2007 Dec 7.
Evaluation of ursolic acid isolated from Ilex paraguariensis and derivatives on aromatase inhibition.
Gnoatto SC, Dassonville-Klimpt A, Da Nascimento S, Galéra P, Boumediene K, Gosmann G, Sonnet P, Moslemi S.
Source Faculdade de Farmácia, Universidade Federal do Rio Grande do Sul (UFRGS), Av. Ipiranga 2752, Porto Alegre 90610-000, RS, Brazil.


Ursolic Acid i media

The Telegraph 2011-07-06
http://www.telegraph.co.uk/health/healthnews/8561592/An-apple-a-day-keeps-your-body-toned-and-slender.html

SVT.se 2011-06-09
http://svt.se/2.58360/1.2449133/utskriftsvanligt_format?printerfriendly=true

Kemivärlden 2011-06-14
http://www.chemicalnet.se/iuware.aspx?pageid=792&ssoid=140385



Publicerad i The Telegraph 2011-07-06
An apple a day keeps your body toned and slender

An apple a day really does keep the doctor away, claim scientists, after finding that they boost muscles and fight fat.
 
It also has health giving properties - reducing blood sugar levels, cholesterol and harmful fatty acids, according to the new study Photo: DANIEL JONES
 By Richard Alleyne, Science Correspondent
6:00PM BST 07 Jun 2011
16 Comments
Researchers have discovered that ursolic acid – a substance found in the peel – has natural body building qualities and could help people keep a toned, slender body.

It could even help with diabetes.

In experiments they discovered that it boosts muscle growth by up to 15 per cent and reduces body fat by more than a half.

It also has health giving properties – reducing blood sugar levels, cholesterol and harmful fatty acids, according to the new study.

Dr Christopher Adams, the study leader at the University of Iowa, said the substance could be especially useful in the elderly who naturally lose body muscle, known as atrophy.


"The old saying goes that 'an apple a day keeps the doctor away'," he said.

"Muscle atrophy causes big problems. It's also very common – it affects most people at some point in their lives, during illness or ageing. But, there's no medicine for it.

"We studied muscle gene activity in people with atrophy and used that information to find chemicals that might block atrophy.

"One of those chemicals was especially interesting. It's called ursolic acid and it's particularly concentrated in apple peels."

The study, published in the latest issue of the journal Cell Metabolism, showed that ursolic acid reduced muscle wasting in mice.

They believe the substance works by reprogramming genes that cause muscle wasting and fat build up.

"Interestingly, although ursolic acid increased muscle weight in mice, it did not increase total body weight, and further investigation showed that mice fed ursolic acid had less body fat than mice that were not fed the compound," he said.

Now they plan to try it on humans to see if it has the same effect.